-Differential diagnosis on clinical grounds
-Differential Diagnosis on dermoscopical grounds
-Origin of SK
- follicular epithelium
- solar lentigo
- Uv exposure
- HPV infection (Human papillomavirus))
- deficiency in presenilin
- vitamin A deficiency
-By hyperproliferation theory
-Accumulation of senescent cells theory
-Pigmentation in SK: a mechanism explained by parallelism?
This review was initially written in 2005 and does not include new discoveries like the proposed fgf3 receptor mutation. However, the information is correct and the publications which came out at later dates do not answer in a definite way the questions made by the study of this frequent albeit enigmatic lesion.
This advice is for informational purposes only and does not replace therapeutic judgement done by a skin doctor.