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Cholesterol and the Skin (Hypercholesterolemia) – Drugs inducing increased cholesterol levels (for professionals)

Drugs used by dermatologists which which can elevate cholesterol levels:

  • Vitamin A derivatives:
  1. Acitretin (and previously etretinate)
  2. Alitretinoin
  3. Isotretinoin




Alitretinoin for the treatment of severe chronic hand eczema. Paulden M, Rodgers M, Griffin S, Slack R, Duffy S, Ingram JR, Woolacott N, Sculpher M. Health Technol Assess. 2010 May;14 Suppl 1:39-46.

Lipid and teratogenic effects of retinoids. Shalita AR. J Am Acad Dermatol. 1988 Jul;19(1 Pt 2):197-8.

Serum lipid elevation during isotretinoin therapy for acne in the west of Scotland. Walker BR, MacKie RM. Br J Dermatol. 1990 Apr;122(4):531-7.

Side-effect profile of acitretin therapy in psoriasis. Gupta AK, Goldfarb MT, Ellis CN, Voorhees JJ. J Am Acad Dermatol. 1989 Jun;20(6):1088-93.

Source of information: here