Call Us : +41 22 738 18 48

Does Common Balding Increase the Risk of developing Diabetes and Cardiovascular Problems ?

Take Home Message: Metabolic syndrome is present in around 15% of males with Androgenetic Alopecia (AGA) and at a younger age (Study from Thailand) (Metabolic Syndrome increases diabetes and cardiovascular risk although the title is written as a question mark)

Comments:
-Metabolic syndrome is defined by the following: at least three of five of the following medical conditions: abdominal (central) obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low high-density lipoprotein (HDL) levels.
-Studies have already shown association between AGA and Ischemic Heart disease
-General information on Hair loss: click HERE   

Abstract
Background: Despite its association with androgenetic alopecia (AGA), the prevalence and patterns of metabolic syndrome (MS) are nonetheless controversial in Thai male AGA patients.
Objectives: To determine the prevalence and patterns of MS in Thai male AGA patients.
Methods: A cross-sectional study was conducted at Chulalongkorn Hospital, Bangkok, Thailand in 30 Thai male AGA patients, aged 20–60 years, with Norwood classification IIIv-V during June 2013. MS was diagnosed according to National Cholesterol Education Program (NCEP) ATP III criteria.
Results: All of the patients with mean (SD.) age of 37.7 (10.3) years and Norwood classification III (26.7%), IV (40%) and IV (26.7%) were enrolled. MS were present in 13.3%, interestingly at a younger age (33.8(3.1) vs 38.3(10.9) years, p=0.099). MS was significantly associated with higher BW (92.5(13.2) vs 69.9(9.5) kg., p<0.001), BMI (30.4(1.0) vs 24.4(2.8) kg/m2, p <0.001), waist cirumference (101.6(6.2) vs 86.1(7.7) cm, p=0.001), hip circumference (104.5(6.8) vs 95.3(7.7) cm, p=0.033), waist/hip ratio (1.0(0.1) vs 0.9(0.1), p=0.019), AST (52.0(28.4) vs 24.5(10.4) IU/ml, p=0.026), and ALT (113.0(65.3) vs 27.2(14.8) IU/ml. Also, more prevalence of BW > 80 kg (100% vs 11.5%, p=0.001), WC > 90 cm (100% vs 26.9%, p=0.012), Triglycerides > 150 mg/dL (75% vs 4%, p=0.004), AST > 40 IU/ml (75% vs 11.5%, p=0.018), and AST > 40 IU/ml (75% vs 15.4%, p=0.031) was related to MS.
Conclusion: The prevalence of MS is 13.3% in Thai male AGA patients with high blood pressure, high waist circumference, and impaired fasting blood sugar. Early detection is thus recommended to prevent cardiovascular diseases.

Reference: Regional Congress of Dermatology (RCD) 2016 – Singapore. RCD16-0057 Hair and nail disorders (including hair loss, onychomycosis) PREVALENCE AND PATTERNS OF METABOLIC SYNDROME IN THAI MALE ANDROGENETIC ALOPECIA PATIENTS S. Lueangarun1, T. Tempark2, R. Panchaprateep3 1Thammasat University, Division of Dermatology- Chulabhorn International College of Medicine, Klonglung, Thailand 2King Chulalongkorn Memorial Hospital, Department of Pediatrics, Bangkok, Thailand 3King Chulalongkorn Memorial Hospital, Division of Dermatology- Department of Medicine, Bangkok, Thailand