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Kojic acid

  • It is a fungal metabolite which inhibits the enzyme tyrosinase.
  • It binds to copper which becomes unusable by melanocytes.
  • It is used at a concentration of 1%
  • Its therapeutical effets are weak to moderate.

 

 

Bibliography: Katsambas A. Melasma: Pathogenesis and Treatment. 70th Annual Meeting of the AAD (American Academy of Dermatology) – San Diego, California, United States of America (USA)

Source of information: here