- It is a fungal metabolite which inhibits the enzyme tyrosinase.
- It binds to copper which becomes unusable by melanocytes.
- It is used at a concentration of 1%
- Its therapeutical effets are weak to moderate.
Bibliography: Katsambas A. Melasma: Pathogenesis and Treatment. 70th Annual Meeting of the AAD (American Academy of Dermatology) – San Diego, California, United States of America (USA)
Source of information: here