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Merkel cells

  • Merkel cells are cells located in the deep epidermis (close to eccrine sweat gland openings (ridges)).
  • The cells communicate with free nerve endings and allow sensation of touch – they are also called Tactile receptors.
  • They allow to discriminiate shapes and textures.
  • Merkel Cells are involved in a rare but aggressive cancer called Merkel Cell Carcinoma.
  • Note: the cell of origin is unknown but could be derived from the neural crest.