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Pacinian Corpuscle (Lamellar Corpuscle; structure)

  • Lamellar Corpuscles (Pacinian corpuscles) are mechanoreceptors containing nerve endings and are located in the dermis.
  • They only react to sudden disturbances, allowing us to sense vibration and for example do distinguish a smooth from a rough surface.
  • Structurally speaking, they consist a capsule (free nerve ending, modified Schwann Cells and flat Epithelial cells) surrounding by layers of fibroblasts + connective tissue in an “onion peel” fashion, but with 50 layers ! Each layer is separated by viscous water.