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Pompholyx or Dysidrosis ?

  • The Greek word of origin is:
    • πομφολυξ = pompholyx = vesicle



  • This term was given to what is now pemphigus by Robert Willan (a British physician, 1757-1817, the real founder of dermatology).
  • Alibert (a French physician, 1766-1837) decided then to use this term for all bullous skin conditions originating from pemphix.
  • This term will persist and afterwards this term will be used to describe vesicles on the hands (cheiro-pompholyx) and on the feet (podo-pompholyx). (considered as a type of endogenous eczema)
  • Nowadays, this term is also known as dysidrosis and pompholyx is rather used for the presence of bullae when the vesicles merge. (often dysidrosis is spelled as dyshidrosis)



Source of information:

-Harms M. Dermatologica Helvetica (The Swiss Journal of Dermatology and Venereology:

Original article: here