They are closely linked to hair follicles and secretions are liberated in its space: the secretion is called (=oiliness of the skin). Sebaceous glands communicate with hair follicles and are mostly located on the face: this is commonly known as the Pilo-sebaceous unit.
Acne is dependent on 3 factors: Bacteria (Propionibacterium Acnes), Hormones (Androgens) and Oily skin (Sebaceous Glands). All three particpants contribute to the liberation of inflammatory mediators.
Sebaceous glands are the target of oral isotretinoin, it reduces the size and 4 to 8 months sebum suppression is becoming the new evaluation of treatment duration; to read more, click HERE.