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Solar lentigo (sunspots, liver spots) and Fat Intake

  • Solar lentigo (sunspots, liver spots) are early seborrheic keratosis and are found in many individuals starting 45-50 years old.
  • They are the result of sun exposure (photodamage).
  • The goal of this study is to investigate the link between fat intake and the severity of solra lentigo.



  • The study was done in 279 women:
    • The severity of lesions (forehead, cheeks) was evaluated a dermatologist and graded from 0 to 6.
    • Fat intake habits were assessed over a period of 24 hours and the type of fat was specified:
  1. total fat
  2. saturated fatty acids
  3. monounsaturated fatty acids
  4. polyunsaturated fatty acids (linoleic, α-linolenic, arachidonic, eicosapentaenoic, n-3 docosapentaenoic and docosahexaenoic acids)
  • Results show (taking into account confounding factors) that solar lentigo are LESS severe when monounsaturated fatty acids and arachidonic acid is high.



  • Comment from authors: the mechanism is not understood and further studies are needed.



Bibliography: J Latreille,1 K Ezzedine,2,3 E Kesse-Guyot,2 R Jdid,1 V Andreeva,2 D Malvy,4 P Galan,2 E Tschachler,1,5 C Guinot1,6 and S Hercberg2,7 1CERIES, Neuilly sur Seine, France, 2UMR U557 INSERM/U1125 INRA/CNAM, University Paris 13, Bobigny, France, 3Dpt Dermatol, CHU Saint-André, Bordeaux, France, 4Dpt Internal Med Trop Dis, CHU Saint-André, Bordeaux, France, 5Dpt Dermatol, Med University Vienna, Vienna, Austria, 6Comput Sci Lab, University François Rabelais, Tours, France and 7Dpt Public Health, Hosp Avicenne, Bobigny, France. Dietary fat intakes are associated with the risk for severe solar lentigines in middle-aged caucasian women. International Investigative Dermatology (IID) 2013 – Edinburgh, United Kingdom

Original article: here