Lymphocytes are inflammatory cells derived from the bone marrow.
Different types exist, B Lymphocytes which secrete antibodies, T helper lymphocytes which secrete cell signalling molecules (cytokines) which regulate inflammation, T cytotoxic lymphocytes which “kill” directly, Natural killer cells (NK) and Gammadelta cells.They are differentiated by the receptors present on the cell surfaces.
They are normally present as infiltrates in the dermis (they invade the epidermis in some cancers = epidermotropism).
They are deeply involved in the development of skin diseases, particularly inflammatory ones.
Skin conditions where involved in Eczema (Dermatitis), Psoriasis and cancers such as lymphomas.