- Neutrophils are cells derived from the bone marrow which are involved in acute inflammation.
- They are the first cells to arrive to combat an infection and in wound healing.
- They are also present in Neutrophilic dermatosis when infectious agents are not present.
- They are metabolically very active in particular in the synthesis of proteins, therefore there is a lot of replication going on in the DNA – as a result of this they display progressively more and more DNA segments (poly-lobulated)
- They have something to do in the development of autoimmunity: they liberate NETs (Neutrophil Extracellular Traps) of DNA to “paralyze” invaders and in doing this expose cell components which are otherwise “invisible” to the body’s own defense system.