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A JAAD Case Reports publication: click HERE for free full article (selected by Dr Christophe HSU, MD  – Dermatologist. Geneva, Switzerland)   Comments Methotrexate is a useful drug in the treatment of psoriasis and can be given orally or injected. To read general information... READ MORE

Take Home Message: 17% of patients on methotrexate develop mild fibrosis with a cumulative dose ranging from (1.4 to 3.3g). The drug appears to be safe as none of the patients developed worse liver damage (see comments and abstract) (Study from Malaysia)   Comments:... READ MORE

Take Home message: Methotrexate (MTX) is often supplemented with folic acid like ANY other systemic drug (oral or injected) can induce toxiderma which presented here on the skin as erosive dermatitis (along with systemic symptoms)…unrecognized, it was lethal 13 days after the... READ MORE

To read the current issue of Dermatologica Helvetica, click HERE (Journal Club, Focus and “What’s Hot” in English) Published in Dermatologica Helvetica (article selection: Prof SAURAT JH, MD – Dermatologist. Geneva, Switzerland) READ MORE

Votre médecin vient de vous prescrire le méthotrexate. Pourquoi utilise t-on le méthotrexate ? Le méthotrexate est un médicament utilisé pour traiter le psoriasis, mais il est également utilisé dans le traitement de beaucoup d’autres maladies. Dans les psoriasis, les cellules se... READ MORE

Monitoring patients on methotrexate: hepatic fibrosis not seen in patients with normal serum assays of aminoterminal peptide of type III procollagen. Maurice PD, Maddox AJ, Green CA, Tatnall F, Schofield JK, Stott DJ. Br J Dermatol. 2005 Mar;152(3):451-8.    ... READ MORE

Your doctor has just prescribed methotrexate for you. What is methotrexate used for? Methotrexate is a medicine used to treat psoriasis. It is also used for many other diseases In Psoriasis, your skin cells grow and mature too rapidly, resulting in elevated, red plaques covered... READ MORE

Diagnostic accuracy of noninvasive markers of liver fibrosis in patients with psoriasis taking methotrexate: a systematic review and meta-analysis. Maybury CM. et al. Br J Dermatol. 2014 Jun;170(6):1237-47. doi: 10.1111/bjd.12905. In classical textbooks it is said that because of... READ MORE

Take Home Message: Dapsone can be used in the Management of Generalized Pustular Psoriasis (Von Zumbusch) (Case Report from Indonesia)   Comments: -Von Zumbusch generalized pustular psoriasis is a systemic inflammatory pustular psoriasis reaction (Localized pustular... READ MORE

Lupus Treatment with Antimalarials: before changing treatments, it is better to increase dosage  Age spots: is a Targeted Treatment on its way ? (Seborrheic Keratosis)  Cancers Metastasizing to the Skin: the presence of some White Blood Cells creates a favorable environment (Treg... READ MORE