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Adalimumab is a monoclonal antibody against TNF. It is currently approved for the treatment of psoriatic and rheumatoid arthritis and ankylosing spondylitis. Dosing is 40 mg subcutaneously every other week. Phase III trial results showed excellent results in the treatment of... READ MORE

Infliximab is a chimeric monoclonal antibody against TNF, with human constant regions and murine variable regions. Studies have shown that it is the most effective biologic agent for the treatment of psoriasis at the usually prescribed doses. Since dosing is weight-based (start... READ MORE

Etanercept is a fusion protein consisting of two tumor necrosis factor (TNF) receptors linked to the Fc protein of human immunoglobulin (IgG). It works by inhibiting the pro- inflammatory action of TNF in psoriasis. Patients inject the medication subcutaneously, with dosing... READ MORE

Treatment of psoriasis is step by step: The base and most important is education and support Then comes topical treatment Then comes systemic treatment and/or phototherapy     Does UVB (Ultraviolet type B) have a role to play in the treatment in psoriasis? US Survey on... READ MORE

Increased risk of diabetes mellitus in relation to the severity of psoriasis, concomitant medication, and comorbidity: a nationwide population-based cohort study. Lee MS, Lin RY, Lai MS. J Am Acad Dermatol. 2014 Apr;70(4):691-8. doi: 10.1016/j.jaad.2013.11.023. Epub 2014 Jan 9.... READ MORE

side effects of phototherapy with NBUVB: In the treatment of Psoriasis: no increase in incidence of BCC (Basal Cell Carcinoma), SCC (Squamous Cell Carcinoma) or Melanoma. Slight increase in incidence of BCC when treatment combined with PUVA. in the treatment of Vitiligo: long... READ MORE

Posts here were written before June 2015. For posts after this date, please go to “Conference Notes” and “Publications in the Scientific Literature” under “Psoriasis”     Clinical Features (2) Auspitz Sign  Features on Dermoscopy (Plaque type) Differentiation with... READ MORE

For articles before June 2015: click here. Psoriasis: it’s Good to Exercise Genital Involvement in Psoriasis: Common and Burdensome Monitoring for Patients on Methotrexate Features on Dermoscopy (Plaque type) Moderate-to-severe forms are much more itchy than previously... READ MORE

Psoriasis is a skin condition which involves 2% of the population. Its causes include environmental and genetic factors. It can be localized or extensive and treatment ranges from topical to systemic agents. Beyond the dermatologist, who is often the only physician psoriasis... READ MORE

Psoriasis is a frequent inflammatory dermatosis which affects 1 to 2% of the global population. It is more frequent in Scandinavia and Europe. It is less frequent in Blacks and Chinese and is a rarity in Ethnic American-Indian population. Its cause is genetic (PSOR1 gene on... READ MORE