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This study suggests an objective way to follow-up of rhododenol-induced vitiligo by skin absorption spectrum analysis A word on Rhododenol (Rhododendrol): Rhododendrol (Rhododenol) is is derived from the white birch tree it inhibits tyrosinase activity and melanin synthesis... READ MORE

Not all consumers developed white blotching after applying rhododendrol (rhododenol)-containing products All treatment areas didn’t necessarily develop white blotchingThe authors performed cell cultures on normal human melanocytes Results high doses (1500micromol and... READ MORE

Le Rhododénol est aussi appelé 4-(4-hydroxyphenyl)-2-butanol. Il est fabriqué par la marque de cosmétiques japonaise Kenebo est est sur le marché depuis 2008. Il est naturellement produit et est approuvé pour le soin de troubles hyperpigmentaires (Chloasma, Masque de Grossesse,... READ MORE

Rhododendrol (Rhododenol, RD) created a big problem in Japan, when 14000 induced cases of vitiligo-like lesions were reported. It is known that Rhododenol is cytotoxic against melanocytes in a Tyrosinase-dependent way.     The authors suggest a new mouse model for the... READ MORE

Rhododenol (Rhododendrol) is phenolic compound known to induce leucoderma. Another similar compound causing this is hydroquinone monomethyl ether The authors did a study in human melanoma B16f10 cells: Rhododenol 4, 4-hydroxyphenyl (R44HPB) 2-butanol increased The ROS (Radical... READ MORE

Rhododenol is also called 4-(4-hydroxyphenyl)-2-butanol. It is manufactured by Kanebo cosmetics and has been on the market since 2008. It is naturally produced and has been approved for the management of pigmentary problems (Melasma, Sun spots, Lentigo…) It is a phenolic compound... READ MORE

Why does it happen ? It’s often the fault of phenols Like monobenzone, chemicals that induce vitiligo are mostly phenols, which contain a benzene ring with hydroxyl group attached. Examples include: 4-tert-butylcatechol 4-tert-butylphenol Mechanism: chemical phenols appear... READ MORE

On connaît des effets toxiques à court terme et à long terme   A court-terme: ochronose exogène Il s’agit d’un effet secondaire possible lors d’une utilisation prolongée de l’hydroquinone, surtout lorsque les concentrations dépassent 4%. Ces effets ont été aussi décrits pour... READ MORE

Le sommaire ci-dessous est en anglais. Pour accéder aux articles en français, cliquer sur “(français)” à la fin de chaque titre.     Characteristics of pigmentary disorders within population groups Acne in Individuals with Colored Skin (français) Acne in... READ MORE

Posts here were written before June 2015. For posts after this date, please go to “Conference Notes” and “Publications in the Scientific Literature”under “Pigmentation”.     Characteristics of pigmentary disorders within population groups Acne in Individuals with... READ MORE