Pigmentation

Posts here were written before June 2015. For posts after this date, please go to “Conference Notes” and “Publications in the Scientific Literature”under “Pigmentation”.

Characteristics of pigmentary disorders within population groups

• Acne in Individuals with Colored Skin 
• Acne in skin of color: Practical Facts 
  Hyperpigmentary Disorders in Caucasians
• Pigment Characteristics in the Caucasian Population
• Pigmentary disorders of the skin during Pregnancy
• Rosacea in individuals with skin of color 
• Pigmentation around the Eyes in Singapore
• Cosmetic Pigmentary Concerns in Singaporeans

Controversy:

• The problem with the skin whitening market

Diagnostic tools & Research:

• Confocal Microscopy 
• Studying Postinflammatory Hyperpigmentation (PIH) on human skin
• A tool to study Rhododenol (Rhododendrol) induced leucoderma (Vitiligo-like lesions) 
• Pigment Research Using In Vitro Models
• Wood’s light: How does it work ? 

Melasma (Chloasma, Pregnancy Mask)

Physiology and Pathophysiology (Hyperpigmentation and Hypopigmentation):

• Pigmentary Anomalies Along Blaschko’s Lines Secondary To Mosaicism 
• Pigmentation: The Role of Blood Vessels 
• Dark Circles Around The Eyes: Why ? 
• Skin Color Regulation By Genes
• The Role of Keratinocytes in Disorders of Pigmentation 
• Melanin:
  • Pigmentation by Melanin and Skin Color 
  • How is melanin produced ? (melanin is the principal pigment giving to the skin its color) 
  • Understanding the Pathways Regulating the Production of Melanin to Conceptualize New Treatments
  • Synthesis of Melanin and its Disturbances 
• Melanocytes:
  • The role of melanocytes in skin pigmentation and how they are regulated 
  • Migration of Melanocytes during Melanogenesis 
• Smoking-Induced Pigmentation: Why ?
• Solar lentigo (sunspots, liver spots) and Fat Intake

Pigmentary Disorders:

• Hyperpigmentation:
  • A reminder of bleomycin-induced hyperpigmentation 
    Hori’s Nevus (Bilateral Acquired Nevus of Ota) 
• Hypopigmentation:
  • « Albinism »: in fact a symptom part of Albinism and of a number of syndromes 
  • Hypopigmentary Disorders in Children (2)

Treatment of Pigmentary Disorders:

• Treatment of Hyperpigmentation
  • Acne Vulgaris: how to treat acne AND hyperpigmentation with one product ? 
  • Treatment of Axillary Hyperpigmentation ? 
  • Chemical Peels to Treat Pigmentary Disorders 
  • Depigmentation: Ebselen and Retinaldehyde ? 
  • What’s new in depigmenting molecules ? (Presentation: Scientific Conference in 2010) 
  • Skin Whitening: Comparing Hydroquinone with a Combination of Ellagic/salicylic Acids
  • Hydroquinone (1) (2) :
    • Hydroquinone To Treat Post-Inflammatory Hyperpigmentation Caused By Acne Vulgaris 
    • Side effects:
      • Is Hydroquinone (HQ) safe ?
      • Ochronosis:
        • Using Hydroquinone and Ochronosis 
        • Using Dermoscopy To Recognize Hydroquinone-Induced Exogenous Ochronosis 
        • Is Ochronosis when treating with Hydroquinone rare ?
        • Exogenous Ochronosis (EO) 
      • Hydroquinone toxicity
    • Topical isonicotinic acid hydrazide (isoniazid) as a new skin depigmenting compound 
    • Lasers:
      • Lasers to treat Pigmentation 
      • Indications of Laser Treatment for Pigmentary Disorders 
      • The Newer Lasers to treat Tattoos and Pigmentary Disorders: Picosecondlasers 
    • Lignin Peroxidase: a cosmeceutical to treat hyperpigmentation 
    • Treatment of post-inflammatory Hyperpigmentation (PIH) in Caucasians 
    • Practical rules for the Treatment of Pigmentation Disorders 
    • Treatment of Solar Lentigines in Caucasians
    • L-ascorbic acid (Vitamin C)
    • Rhododenol (Rhododendrol):
      • Rhododenol (Rhododendrol)-induced leukoderma: an objective way to ascertain normalization of the skin
      • Rhododenol-induced cyotoxicity: proposed mechanism of action 
      • Rhododenol (Rhododendrol) – induced toxicity appears to happen at higher concentrations and the protective mechanism it triggers 
      • Soy derived products to depigment the skin
      • Validamycin A could inhibit the production of melanin
• Treatment of Hypopigmentation
  • Pigmenting the skin with injections of Afamelanotide (Melanotan) (Scenesse) 
  • Coloring the Skin 
  • Phototherapy: How does it work ? 

• Vitiligo