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filaggrin

How skin pH could affect disease activity in Atopic Dermatitis

Atopic Dermatitis (AD), beyond filaggrin mutations is better understood, but still remains (at the time of publication) full of gaps. pH alterations in AD are a matter of debate, but they do have an effect on its symptoms (itching) and appearance. This study shows molecular as...
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Keratosis Pilaris (For Professionals)

Keratosis pilaris is a very frequent condition: It presents as follicular scaly papules affected all areas except the glabrous skin but mostly found on the arms, legs and buttocks. These lesions are painless but may be red and itchy at times.     It is associated with...
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L’ichtyose vulgaire

L’ichtyose vulgaire vue de près     Qu’est-ce que l’ichtyose vulgaire ? Il s’agit d’une affection héréditaire (Autosomique Dominante). Elle touche une personne sur 250.     A quoi est-ce que ça ressemble ? L’ichtyose vulgaire apparaît comme des écailles de...
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Problèmes de peau chez les jeunes enfants

Dermatite atopique     1. La dermatite atopique – qu’est-ce que c’est? La dermatite (ou eczéma) atopique est une inflammation sèche et prurigineuse (qui gratte) de la peau. C’est l’affection cutanée la plus fréquente chez l’enfant. Il ne s’agit pas d’une maladie...
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Eczema et Dermatite Atopique

Qu’est-ce que c’est l’eczéma et la dermatite? Eczéma et dermatite ont la même signification. L’eczéma est une des causes les plus fréquentes de peau sensible et sèche. Le mot eczéma provient du grec et signifie bouillir en surface. C’est une description précise de lésions...
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What’s New In The Pathogenesis And Prevention Of Extrinsic Aging (Ageing) (Photoaging)

Photoaging (Extrinsic Aging, solar elastosis)     Skin Aging can be Understood by considering two concepts Cumulative acute stress through chronic mechanisms: three stages degeneration of macromolecules Altered cell function Modified Structure and function of organs Mt...
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Ichthyosis Vulgaris

Education – Table of Contents Ichthyosis Vulgaris: close-up     What is ichthyosis vulgaris ? It is an inherited condition (Autosomal dominant pattern) It affects one in 250 people.     What does it look like ? It causes dry scaly plaques. The lesions...
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Germs living on normal Skin and the changes observed in Atopic Dermatitis (Microbiome)

Abbreviations: AD=Atopic Dermatitis -The Microbiome is in fact microbiota and this terms designates the community of germs (bacteria, viruses and fungi) present since birth -The amount of the total human microbiome amount to approximately 1.5Kg (1-3% of the body mass) -Microbiota...
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The role of the pH in breaking the skin barrier in Atopic Dermatitis

Abbreviations: AD: Atopic Dermatitis BACKGROUND -The Skin barrier is essential in maintaining normal skin -Increased skin surface pH in the acute phase induces breakdown of the skin barrier. -In AD the following is found in the upper epidermis defective lipid lamella: this...
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Dry Skin: The Upper Part of Epidermis is Thickened

Characteristic differences in barrier and hygroscopic properties between normal and cosmetic dry skin. I. Enhanced barrier analysis with sequential tape-stripping. Lu N. et al. Int J Cosmet Sci. 2014 Apr;36(2):167-74. doi: 10.1111/ics.12112. Epub 2014 Jan 31. People with Atopic...
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