Search

Nivolumab in previously untreated melanoma without BRAF mutation. Robert C. et al. N Engl J Med. 2015 Jan 22;372(4):320-30. doi: 10.1056/NEJMoa1412082. Epub 2014 Nov 16. INTRODUCTION Malignant Melanoma (MM) is the most deadly of skin cancers and advanced melanomas need... READ MORE

Congenital Melanocytic Nevus (Naevus)(CMN) These are melanocytic naevi (nevi) (“moles”) which are present at birth. The melanocytic naevi vary greatly in size but can exceed 20cm of diameter. They are generally located on the trunk. They can develop into cancers (melanoma).... READ MORE

Melanoma often goes undetected, especially in children. Indeed, because of its lower incidence there is often a low index of suspicion. Melanoma detection is a well-established science and the ABCDE criteria is a well established technique (combining wth dermoscopy if possible).... READ MORE

This is a cancer of the pigment cells of the skin. It is a highly malignant skin cancer. It presents as dark brown or black skin growth or ulcer. It may look like ordinary moles. But unlike the common mole: it grows rapidly its surface has several shades of red, black or blue... READ MORE

Acne Alopecia  Alopecia Areata  Blotchiness (Early Rosacea) Eczema (Dermatitis) Eschar (Pressure Ulcer) Herpes Impetigo Itch (Pruritus)  Keloid Lichen Planus Lupus Erythematosus  Melanoma  Nevus (Mole, Naevus)  Psoriasis  Tattoo Shingles Urticaria (hives) Vitiligo   -Viewed... READ MORE

-This lesion can be present at birth (congenital). -It can be lightly pigmented or black. -It needs to be monitored, and regularly check by a dermatologist with a dermatoscope -In case of change in size, color, or shape, it should be removed and analyzed under a microscope. -To... READ MORE

A JAAD Case Reports publication: click HERE for free full article (selected by Dr Christophe HSU, MD  – Dermatologist. Geneva, Switzerland)   Comments Squamous Cell Carcinoma (SCC) is a Keratinocytic Carcinoma – Previously it was called Non-Melanoma Skin Cancer NMSC... READ MORE

Microtubules are thick diameter (25 nanometers) intracellular structures which appear as straight rods when viewed under electron microscopy. They are dynamic structures which can collapse and reform within seconds. Microtubules form the framework of the cell division spindles... READ MORE

Take Home Message: There is a trend of the usefulness of retinoids in the prevention of non-melanoma skin cancers (NMSC, now called Keratinocyte Carcinoma). However the results are NOT statistically significant (see comments) (Study from the Philippines)   Comments... READ MORE

Take Home Massage: The term “Dysplastic Nevus” refers to a clinical lesion (an atypical mole) as well as a clinical presentation (Dysplastic Nevus Syndrome). It also refers to a histological diagnosis (somewhere between a nevus and malignant melanoma) and the term in... READ MORE